Trend Micro's Virus Scan API (VSAPI) and Advanced Threat Scan Engine (ATSE) - are vulnerable to a memory exhaustion vulnerability that may lead to denial-of-service or system freeze if exploited by an attacker using a specially crafted file.

Buffer overflow in the Trend Micro Scan Engine 8.000 and 8.300 before virus pattern file 4.245.00, as used in other products such as Cyber Clean Center (CCC) Cleaner, allows remote attackers to execute arbitrary code via a malformed UPX compressed executable.

Heap-based buffer overflow in Trend Micro AntiVirus Library VSAPI before 7.510, as used in multiple Trend Micro products, allows remote attackers to execute arbitrary code via a crafted ARJ file with long header file names that modify pointers within a structure.

Trend ScanMail allows remote attackers to obtain potentially sensitive information or disable the anti-virus capability via the smency.nsf file.