The Crypto.Random.atfork function in PyCrypto before 2.6.1 does not properly reseed the pseudo-random number generator (PRNG) before allowing a child process to access it, which makes it easier for context-dependent attackers to obtain sensitive information by leveraging a race condition in which a child process is created and accesses the PRNG within the same rate-limit period as another process.

PyCrypto before 2.6 does not produce appropriate prime numbers when using an ElGamal scheme to generate a key, which reduces the signature space or public key space and makes it easier for attackers to conduct brute force attacks to obtain the private key.