On F5 BIG-IP 13.1.x versions prior to 13.1.5, and all versions of 12.1.x and 11.6.x, when multiple route domains are configured, undisclosed requests to big3d can cause an increase in CPU resource utilization. Note: Software versions which have reached End of Technical Support (EoTS) are not evaluated

On BIG-IP versions 11.6.0-11.6.2 (fixed in 11.6.2 HF1), 12.0.0-12.1.2 HF1 (fixed in 12.1.2 HF2), or 13.0.0-13.0.0 HF2 (fixed in 13.0.0 HF3) a virtual server configured with a Client SSL profile may be vulnerable to an Adaptive Chosen Ciphertext attack (AKA Bleichenbacher attack) against RSA, which when exploited, may result in plaintext recovery of encrypted messages and/or a Man-in-the-middle (MiTM) attack, despite the attacker not having gained access to the server's private key itself, aka a ROBOT attack.

In F5 BIG-IP LTM, AAM, AFM, Analytics, APM, ASM, DNS, Edge Gateway, GTM, Link Controller, PEM, WebAccelerator software version 12.0.0 - 12.1.2, 11.6.0 - 11.6.1, 11.4.0 - 11.5.4, 11.2.1, when ConfigSync is configured, attackers on adjacent networks may be able to bypass the TLS protections usually used to encrypted and authenticate connections to mcpd. This vulnerability may allow remote attackers to cause a denial-of-service (DoS) attack via resource exhaustion.